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Rabbit Anti-Adenosine A3 Receptor/Gold Conjugated antibody (bs-1225R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-1225R-Gold
英文名稱 Rabbit Anti-Adenosine A3 Receptor/Gold Conjugated antibody
中文名稱 膠體金標記的腺苷受體A3抗體
別    名 adenosine A3 receptor; A3AR; AD 026; AD026; ADORA 3; ADORA3; bA552M11.5; RP11 552M11.7; TGPCR1; adenosine receptor A3 isoform 1; adenosine receptor A3 isoform 2; AA3R_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 心血管  神經生物學  細胞膜受體  G蛋白偶聯受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADORA3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.

Subcellular Location:
Cell membrane.

Post-translational modifications:
Phosphorylation on Ser-317 may be crucial for rapid desensitization.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 403805 Dog

Entrez Gene: 140 Human

Entrez Gene: 606753 Pig

Omim: 600445 Human

SwissProt: Q28309 Dog

SwissProt: P33765 Human

SwissProt: Q6P2N6 Human

Unigene: 281342 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ADORA-3(腺苷受體A3)屬于G蛋白偶聯受體家族,在腺苷調節細胞活力和生長中起關鍵作用,并且在很多腫瘤中表達增高,A3AR可能成為腫瘤診斷標志物和治療靶點。
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